Migraine

Evidence-based guidelines for the pharmacological treatment of migraine

Raffaele Ornello, Valeria Caponnetto, Fayyaz Ahmed, Haidar M. Al-Khazali, Anna Ambrosini, Sait Ashina, et al.

Abstract

International evidence-based recommendations for medicines used to treat migraine, published in Cephalalgia in 2025.

This Cephalalgia guideline summarises evidence-based pharmacological treatment of migraine, including medicines used for acute attacks and for prevention. Pakistan Headache Society highlights the 2025 open-access record so clinicians can reach the official journal version.

Full recommendation statements should be read on the publisher site. This page is a PHS summary and citation, not a republication of the article.

Citation

Ornello R, Caponnetto V, Ahmed F, Al-Khazali HM, Ambrosini A, Ashina S, et al. Evidence-based guidelines for the pharmacological treatment of migraine. Cephalalgia. 2025;45(4). doi:10.1177/03331024241305381

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